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ARID3B

From Wikipedia, the free encyclopedia
ARID3B
Identifiers
AliasesARID3B, BDP, DRIL2, AT-rich interaction domain 3B
External IDsOMIM: 612457; MGI: 1930768; HomoloGene: 4721; GeneCards: ARID3B; OMA:ARID3B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001307939
NM_006465

NM_019689
NM_001379353

RefSeq (protein)

NP_001294868
NP_006456

NP_062663
NP_001366282

Location (UCSC)Chr 15: 74.54 – 74.6 MbChr 9: 57.7 – 57.74 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

AT-rich interactive domain-containing protein 3B is a protein that in humans is encoded by the ARID3B gene.[5]

Function

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This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000179361Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000004661Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: ARID3B AT rich interactive domain 3B (BRIGHT-like)".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.