Prosulfocarb
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| Names | |
|---|---|
| IUPAC name
S-Benzyl N,N-dipropylcarbamothioate
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| Other names
Prosulfocarb
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| Identifiers | |
| ECHA InfoCard | 100.100.363 |
PubChem CID
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CompTox Dashboard (EPA)
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|
| Properties | |
| C14H21NOS | |
| Molar mass | 251.39 g·mol−1 |
| Appearance | Colourless - pale yellow |
| Odor | Aromatic |
| Density | 1049 kg/m3[1] |
| Melting point | -20 °C[3] |
| Boiling point | 341 °C[3] |
| Insoluble[3] | |
| Solubility in xylene | Soluble[3] |
| Solubility in acetone | Soluble[3] |
| Solubility in heptane | Soluble[3] |
| Solubility in ethyl acetate | Soluble[3] |
| Vapor pressure | 0.79 mPa[3] |
| Hazards | |
| GHS labelling: | |
 
| |
| Warning | |
| H227, H302, H317, H335, H371, H373, H401 | |
| Flash point | 167.1 °C[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Prosulfocarb is a pre-emergent herbicide used agriculturally in Australia, the EU, Morocco[3] and Iran, for control of annual ryegrass and toad rush in wheat and barley crops.[4] It was introduced to the EU in 1988 and is rapidly growing in use, with sales increasing by over 500% in France since 2008.[5]
Prosulfocarb is a thiocarbamate, and is absorbed by the roots of germinating seedlings to inhibit growth in the meristem by inhibiting fat synthesis.[6]
Application
[edit]To target annual ryegrass, 2.5L/ha (of 800 g/L emulsifiable concentrate) is prepared and sprayed before sowing. It can be applied to barley post-emergence, but if applied wrongly may cause crop damage.[7] Prosulfocarb does not need much moisture to be applied efficably, due to low volatility.[8]
Prosulfocarb is often applied alongside s-Metolachlor and pyroxasulfone, or in Australia with trifluralin, with which it more efficiently circumvents weed resistance.[9]
Safety and Environmental Effect
[edit]Prosulfocarb's LD50 toxicity is 1820 mg/kg orally for rats,[2] which is comparable to paracetamol. The human toxicological effect is low.[5] Prosulfocarb itself is not a combustible, but formulations can be due to other components. (e.g. solvent naphtha)[10] Prosulfocarb is an irritant.[3]
Prosulfocarb is toxic to aquatic organisms; it is mandatory in Australia not to spray it within 20 metres upwind of aquatic or wetland areas or to apply by air. Nor if heavy rain is expected, to prevent runoff.[6] It is not persistent in soil, with a halflife of 35 days. Prosulfocarb bioaccumulates, and has slight mobility in soil.[10]
Production
[edit]Global herbicide production is in TGAC form, typically 95-98% purity, whence it is shipped and locally formulated into commercially practical formulations, a mix with a solvent such as solvent naptha[10] and other agents to make good mixing behaviour. Tech production is often in the USA, Japan, China, and India, the top four global agrochemical producers.[11] Hermani, in Bharuch, India, has the capacity for 5000 tonnes of technical per year; Punjab Chemicals, in Dera Bassi, another 3000;[12] Weifang Sino-Agri, China, another 1000 tonnes per year.[13]
Lists
[edit]These lists are non-exhaustive.
Prosulfocarb has been used to control the following weeds: Annual ryegrass, Lolium rigidum,[6] which is highly resistant to other herbicides, notably glyphosate, Barley Grass, toad rush, Red and White Fumitory, Paradoxa grass (Canary Grass), Phalaris spp, Sand Fescue, Silver Grass (Vulpia spp.), soil surface Wild Oats, Wireweed (Hogweed), suppression of Brome Grass, Deadnettle, Rough Poppy and Yellow Burr Weed.[14]
Prosulfocarb has been applied to the following crops: wheat and barley.[6]
Prosulfocarb has been sold under these tradenames: Prosulfocarb 800, (4Famers, Genfarm, Reylon), Profuse, Arcade, (Syngenta), Countdown, Boxer Gold, (combination with s-Metolachlor), and Dian.
References
[edit]- ^ a b c "Prosulfocarb SDS" (PDF). ChemicalBook. Retrieved 5 August 2024.
- ^ a b "Prosulfocarb Standard SDS" (PDF). FujiFilm. Retrieved 5 August 2024.
- ^ a b c d e f g h i j "Prosulfocarb (Ref: SC 0574)". Pesticide Properties DataBase. Retrieved 8 August 2024.
- ^ "Prosulfocarb 800 Label" (PDF). GenFarm. Retrieved 5 August 2024.
- ^ a b Devault, Damnien; Guillemin, Jean-Philippe; Maurice, Millet; Eymery, Frank (January 2022). "Prosulfocarb at center stage!". Environmental Science and Pollution Research. doi:10.1007/s11356-019-06928-8. Retrieved 5 August 2024.
- ^ a b c d "4Farmers Australia Prosulfocarb Leaflet" (PDF). www.4farmers.com.au. 4Farmers Australia. Retrieved 5 August 2024.
- ^ "4Farmers Prosulfocarb 800 EC Infosheet" (PDF). www.4farmers.com.au. 4Farmers Australia. Retrieved 5 August 2024.
- ^ "Australia - Give your barley growers value through efficacy and flexibility in ARG control". Grainews.
- ^ Kleemann, Samuel G. L.; Preston, Christopher; Gill, Gurjeet S. (2014). "Influence of Seeding System Disturbance on Preplant Incorporated Herbicide Control of Rigid Ryegrass (Lolium rigidum) in Wheat in Southern Australia" (PDF). Weed Technology (28): 323–331. Retrieved 5 August 2024.
- ^ a b c "4Farmers Prosulfocarb Herbicide Safety Data Sheet" (PDF). 4farmers.com.au. 4Farmers Australia. Retrieved 5 August 2024.
- ^ "22 active ingredient patents to expire by 2030: What it means for Indian agrochemical companies". Grainews.
- ^ "Will India's Herbicide Boom Year Continue?". Grainews.
- ^ "Weifang Sino-Agri Union's 1,000-tons prosulfocarb technical project completed". Grainews.
- ^ "Prosulfocarb 800 Label" (PDF). Reylon.
External Links
[edit]- Prosulfocarb in the Pesticide Properties DataBase (PPDB)